Tolcapone Alcohol Interaction



Tolcapone Alcohol

Tolcapone is the generic name of a drug which is used along with levodopa/carbidopa to treat Parkinson disease and is only used in patients who cannot take or have not responded to other medications. It is a catechol-O-methyltransferase (COMT) inhibitor and works by prolonging the anti-Parkinson effect action of levodopa.

It is suggested no alcohol not even moderate drinking while using this drug as the drug’s effectiveness may be decreased and the side effects may be increased.

At this time the medical community defines moderate consumption of alcohol as no more than two drinks per day and no more than 14 drinks per week. If anything more than that it is considered an unhealthy dependency on alcohol that may have adverse social, family and health consequences.

If a person drinks only once or twice a week but drinks on the same days each week and more than two drinks this is considered as an alcohol dependency.

If a person binge drinks at any time during the week this is also considered as alcoholism.

Some consider alcoholism as a disease while others consider it an addiction which is the result of personal choice and character fault. This school of thought blames the alcoholism on life style choices.

Personally I consider alcoholism a genetic tendency as I have seen families of alcoholics even when they live far apart. These unfortunate people are probably dependent on alcohol from the first drink.

When alcohol interacts with prescription over the counter drugs it usually results in negative health effects most especially liver damage as the main organ affected.

Before using this drug advise your doctor if you are allergic to any other drug or substance, if you are using dietary or herbal supplements, are pregnant, plan to be or are breastfeeding, have a history of kidney or liver disease, diabetes, history of severe uncontrolled muscle movements such as uncontrolled jerking, twitching or a severe muscle problem known as rhabdomyolysis or experience dizzy or lightheaded when standing up.

Side Effects

Less serious side effects are diarrhea, dizzy, drowsy, dry mouth, gas, headache, increased sweating, lightheaded when sitting or standing, nausea, stomach upset, trouble sleeping, unusual excessive dreaming, upper respiratory tract infection, urine discoloration or vomiting.. If these occur call your physician for advice.

Serious side effects are severe allergic reactions such as hives difficult breathing, tight chest, swelling of the mouth, face, lips or tongue, black bloody stools, changes in urination, chest pain, confusion, dark urine, depression, fainting, fast irregular heartbeat, fever, chills, sore throat, loss of appetite, mental or mood changes, numb arm or leg, one side weakness, pale stools, red swollen blistered peeling skin, ringing in ears, seizures, severe headache or dizziness, severe persistent stomach pain or nausea, severe vomiting, short of breath, weight gain, swelling of hands, legs or feet, bruising or bleeding, joint or muscle pain, tired or weak, vision or speech problems, granular vomit or jaundice. If these occur get emergency medical help.

This site serves as an information source only and does not dispense medical advice or any other kind of advice. If you are seeking medical advice you are advised to consult your own physician.

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